Emergency Medical Technician (EMT) Basic Certification Practice Exam

What medication is contraindicated when administering nitroglycerin?

1. Ibuprofen

2. Aspirin

3. Erectile Dysfunction medications

4. Acetaminophen

The correct answer is: Erectile Dysfunction medications

Nitroglycerin is commonly used in emergency situations to relieve chest pain or angina by dilating blood vessels and improving blood flow. However, this medication is contraindicated in patients who have recently taken erectile dysfunction medications, such as sildenafil (Viagra), tadalafil (Cialis), or vardenafil (Levitra). The combination of nitroglycerin and these medications can lead to a severe drop in blood pressure, resulting in potentially life-threatening complications. The mechanism of action of these erectile dysfunction medications involves vasodilation, similar to nitroglycerin. When taken together, the cumulative effects can significantly lower systemic vascular resistance and cause hypotension, which can be dangerous, especially in patients already experiencing cardiac issues. Other options provided, such as ibuprofen, aspirin, and acetaminophen, do not have the same risk when administered with nitroglycerin. Aspirin is even commonly used in conjunction with nitroglycerin in the management of cardiac events, as it helps reduce blood clotting. Therefore, the critical contraindication relates specifically to the use of erectile dysfunction medications alongside nitroglycerin.